The Bills were shown in the episode playing the New England Patriots, who are the favorite team of the characters from the show. The game saw the Bills win on a last-second play as part of an episode themed around how God views the Patriots and the characters.
Spiller and Williams were interviewed during the episode. They recorded their parts last year.
The show was a stark reversal from real life. The Patriots have won 25 of the teams' 28 meetings this century. Buffalo last beat New England at home in 2011.Tags: Buffalo, Buffalo Bills, C.J. Spiller, Family Guy, Football, Mario Williams, New England Patriots, NFL